In order to overcome the limitations of traditional university research management system, in order to improve the efficiency of scientific research management and the transformation rate of scientific research achievements in universities, this paper proposes an innovative strategy based on "Internet plus". The innovation strategy has fully developed the advantages of the Internet platform, combined with the "Internet plus" thinking, and achieved the deep integration and organic development of "Internet plus" and scientific research management in universities. The results show that the innovation strategy can realize the transformation of traditional scientific research management system and improve the conversion rate of scientific research achievements.