The outbreak of the epidemic is both a challenge and an opportunity. It has helped bring online education to maturity and changed the norm of education. In the Post-epidemic era, we need to reflect on the problems existing in the "abnormal teaching" during the epidemic period, and comprehensively reconstruct the "new normal" of education in the Post-epidemic period by combining with the "normal teaching" before the epidemic. On this basis, it further promotes the implementation plan of mixed teaching and comprehensively enhances the teaching effect, to provide a certain reference for comprehensive colleges and universities to promote the mixed teaching.